Caracterización de un grupo de pacientes atendidos por masa parotídea en una institución de tercer nivel / Characterization of a group of patients with parotid mass in a tertiary-level hospital

"Introducción: Los tumores de la glándula parótida son un motivo de consulta frecuente en los centros de referencia para patologías de cabeza y cuello. La mayoría son benignos. Sin embargo, requieren manejo quirúrgico por su localización evidente y riesgo de malignización. Objetivo: Describir las características clínicas y demográficas de pacientes con masas parotídeas en nuestra institución. Diseño: Estudio observacional descriptivo tipo serie de casos. Materiales y métodos: Se realizó un estudio descriptivo de los pacientes con diagnóstico de masa parotídea en el Servicio de Otorrinolaringología del Hospital Universitario del Valle entre 01/2011- 06/2014. Resultados: El total de registros fue de 61 pacientes. 20 parotidectomías se realizaron en hombres (32.8%) y 41 en mujeres (67.2%). 7 pacientes (11.5%) tenían 18-30años, 28 (45.9%), 31-50años y 26 (42.6%) más de 50 años. 32 presentaban un tamaño tumoral de 10-39mm (52.5%), 25 (41%) 40-89mm y 3 ≥90mm (4.9%). A 36 se les practicó TAC de cuello (59%). A 47 se les tomó 0BACAF (77%), a 15 TRUCUT (24.6%) y ninguno se llevó a biopsia excisional. El resultado patológico final fue benigno en un 63.9% y maligno en 13.1%. Discusión: Los tumores de parótida son relativamente frecuentes en la consulta Otorrinolaringológica y de Cirugía de Cabeza y Cuello. En nuestro país no encontramos una caracterización de esta entidad y en los pocos centros de referencia, se encontraron datos de patología maligna exclusivamente. Conclusiones: La información presentada abre la posibilidad a estudios ulteriores que permitan definir protocolos de manejo para esta patología en nuestro país. "

"Introduction: The tumors of the parotid gland are a frequent reason for consultation in reference centers for head and neck pathologies. Most are benign. However, a surgical management is required because of their evident location and risk of malignancy. Objective: To describe the clinical and demographic characteristics of patients with parotid masses in our institution. Design: Case series study. Materials and methods: A descriptive study of patients operated on with diagnosis of parotid mass in the Otorhinolaryngology Service of the Hospital Universitario del Valle between 01/2011-06/2014 was carried out. Results: The total of records was 61 patients. 20 parotidectomies were performed in men (32.8%) and 41 in women (67.2%). 7 patients (11.5%) were 18-30 years old, 28 (45.9%), 31-50 years old and 26 (42.6%) >50 years old. 32 had a tumor size of 10-39mm (52.5%), 25 (41%) 40-89mm and 3 ≥90mm (4.9%). A neck CT scan was performed in 36 patients (59%). 47 were underwent a Fine Needle Aspiration biopsy (77%), 15 TRU-CUT (24.6%); excisional biopsy was not carried out. The final pathological result was benign in 63.9% and malignant in 13.1% of the cases. Discussion: Parotid tumors are relatively frequent in the Otorhinolaryngology and Head and Neck Surgery outpatient care. In our country we did not find a characterization of this entity and as for the few reference centers, only malignant pathology data were found. Conclusions: The information presented in this paper opens up the possibility for further studies to define management protocols for this pathology in our country."

Clinical characteristics and HPV type in recurrent respiratory papillomatosis in Colombia.

OBJECTIVE: Describe factors associated with aggressive forms of recurrent respiratory papillomatosis (RRP). MATERIALS AND METHODS: One hundred eighty-nine RRP cases diagnosed between 1985 and 2009 were identified in pathological records. HPV was detected by the SPF-10 method with broad spectrum primers, (version 1). RESULTS: 113 patients had only one surgery (less aggressive) and 76, two or more interventions (more aggressive). The likelihood of aggressive lesions decreased with increasing age at diagnosis and HPV-11 was associated with no significant increase in the risk of aggressiveness. CONCLUSIONS: The age at diagnosis was the main determinant of RRP aggressiveness.

Clinical characteristics and HPV type in recurrent respiratory papillomatosis in Colombia / Características clínicas y genotipo de VPH en papilomatosis respiratoria recurrente en Colombia

Objective. Describe factors associated with aggressive forms of recurrent respiratory papillomatosis (RRP). Materials and methods. One hundred eighty-nine RRP cases diagnosed between 1985 and 2009 were identified in pathological records. HPV was detected by the SPF-10 method with broad spectrum primers, (version 1). Results. 113 patients had only one surgery (less aggressive) and 76, two or more interventions (more aggressive). The likelihood of aggressive lesions decreased with increasing age at diagnosis and HPV-11 was associated with no significant increase in the risk of aggressiveness. Conclusions. The age at diagnosis was the main determinant of RRP aggressiveness.

Objetivo. Describir factores asociados con formas agresivas de papilomatosis respiratoria recurrente (PRR). Material y métodos. Se identificaron 189 casos de PRR diagnosticados entre 1985-2009 en registros patológicos. VPH fue detectado por el método SPF-10 con cebadores de amplio espectro, (versión 1). Resultados. 113 casos presentaron una intervención quirúrgica (menos agresivas) y 76, dos o más intervenciones (más agresivas). La probabilidad de lesiones agresivas disminuyó con el aumento de la edad al momento del diagnóstico y el VPH-11 se asoció con aumento no significativo del riesgo de agresividad. Conclusiones. La edad al momento del diagnóstico fue el principal determinante de la agresividad de PRR.

Human papillomavirus genotype detection in recurrent respiratory papillomatosis (RRP) in Colombia.

BACKGROUND: Knowledge on human papillomavirus (HPV) genotype distribution in recurrent respiratory papillomatosis (RRP) is essential to assess the impact of HPV vaccine. It is provided information for Colombia. METHODS: In all, 189 RRP primary cases diagnosed between 1985 and 2009 were identified from 5 pathology laboratories of Cali and Medellin, Colombia. HPV DNA testing in 129 cases that fulfilled inclusion criteria (available paraffin blocks, amplifiable DNA, and confirmed histologic diagnosis of RRP) was performed by the SPF-10/LiPA25 assay (version 1). RESULTS: Of all cases 36.1% were juvenile (<12 years old) and a majority of adults were males (p = .09); 95% of cases were HPV positive. HPV 6, 11, and 16 contributed to 69%, 27.1%, and 7.8% of all HPV positive cases. Twelve cases (9.3%) showed multiple infections; 8 of these were HPV 6 or 11 positive. CONCLUSIONS: HPV prophylactic vaccine including HPV 6 and 11 may have a major impact against RRP.